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Chair Animal Ecology I (Prof. Dr. Christian Laforsch)

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Team > Dr. Anja Ramsperger

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Overview
ramsperger Dr. Anja Ramsperger
ramsperger

Faculty of Biology, Chemistry and Earth Sciences
Chair Animal Ecology I


PhD candidate Animal Ecology | Supervisor Prof. Dr. Christian Laforsch
PhD candidate Biological Physics | Supervisor Prof. Dr. Holger Kress

PhD project: CRC 1357 Microplastic | Subproject A04 | Cellular uptake of microparticles as a function of elementary particle properties

My PhD project is in the topic area of microplastics within the project PlasticsFateE (Plastics Fate and Effects in the human body) and subproject A04 of the Collaborative Research Centre 1357 Microplastics.

The main objective of PlasticsFatE (Plastics Fate and Effects in the human body) is to improve our current understanding of the effects of micro- and nanoplastics (MP/NP) and associated additives/adsorbed contaminants (A/C) in the human body.

In PlasticsFatE, we are investigating (1) the occurrence of MP/NP in a variety of complex matrices such as food (vegetables, fruits, beverages, fish, etc.), consumer products (toothpaste, cosmetics) and relevant environmental media (air, drinking water, soils); (2) the fate (including long-term) of MP/NP in the human body; and (3) the transport of MP/NP through biological barriers and their potential cytotoxicity. PlasticsFatE is part of the European MNP cluster (CUSP) on human health.

PlasticsFatE is a 48-month project funded by the European Union's Horizon 2020 research and innovation programme. The project will run from 1 April 2021 to 31 March 2025.

More information: https://www.plasticsfate.eu

The Collaborative Research Centre (SFB) 1357: "Microplastics - Laws of formation, transport, physico-chemical behaviour and biological effects: From model to complex systems as a basis for new solutions" researches the formation, migration and effects of microplastics and develops new solutions for this immense environmental problem.

Within the SFB 1357, I am mainly involved in project A04: "Cellular uptake of microparticles depending on elementary particle properties". Different model MP particles as well as model particles for naturally occurring particulate material are incubated in freshwater and soil and resulting surface changes are biomolecularly and physicochemically characterised. Subsequently, different polyelectrolyte multilayer-coated model particles are produced, each of which resembles the incubated particles in one property (e.g. identical mechanics or charge density). By comparing the different particles, the relevance of this property for the adhesion of the particles to cells and the internalisation into cells will be quantitatively investigated.

More information: https://www.sfb-mikroplastik.uni-bayreuth.de

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