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Team > Dr. Anja Ramsperger

ramsperger Dr. Anja Ramsperger

Faculty of Biology, Chemistry and Earth Sciences
Chair Animal Ecology I

PhD candidate Animal Ecology | Supervisor Prof. Dr. Christian Laforsch
PhD candidate Biological Physics | Supervisor Prof. Dr. Holger Kress

PhD project: CRC 1357 Microplastic | Subproject A04 | Cellular uptake of microparticles as a function of elementary particle properties

My PhD project is in the topic area of microplastics within the project PlasticsFateE (Plastics Fate and Effects in the human body) and subproject A04 of the Collaborative Research Centre 1357 Microplastics.

The main objective of PlasticsFatE (Plastics Fate and Effects in the human body) is to improve our current understanding of the effects of micro- and nanoplastics (MP/NP) and associated additives/adsorbed contaminants (A/C) in the human body.

In PlasticsFatE, we are investigating (1) the occurrence of MP/NP in a variety of complex matrices such as food (vegetables, fruits, beverages, fish, etc.), consumer products (toothpaste, cosmetics) and relevant environmental media (air, drinking water, soils); (2) the fate (including long-term) of MP/NP in the human body; and (3) the transport of MP/NP through biological barriers and their potential cytotoxicity. PlasticsFatE is part of the European MNP cluster (CUSP) on human health.

PlasticsFatE is a 48-month project funded by the European Union's Horizon 2020 research and innovation programme. The project will run from 1 April 2021 to 31 March 2025.

More information: https://www.plasticsfate.eu

The Collaborative Research Centre (SFB) 1357: "Microplastics - Laws of formation, transport, physico-chemical behaviour and biological effects: From model to complex systems as a basis for new solutions" researches the formation, migration and effects of microplastics and develops new solutions for this immense environmental problem.

Within the SFB 1357, I am mainly involved in project A04: "Cellular uptake of microparticles depending on elementary particle properties". Different model MP particles as well as model particles for naturally occurring particulate material are incubated in freshwater and soil and resulting surface changes are biomolecularly and physicochemically characterised. Subsequently, different polyelectrolyte multilayer-coated model particles are produced, each of which resembles the incubated particles in one property (e.g. identical mechanics or charge density). By comparing the different particles, the relevance of this property for the adhesion of the particles to cells and the internalisation into cells will be quantitatively investigated.

More information: https://www.sfb-mikroplastik.uni-bayreuth.de


Faculty of Biology, Chemistry and Earth Sciences
Chair Animal Ecology I

Master in Biodiversity and Ecology

PhD candidate: Animal Ecology & Biological Physics | Supervisor Prof. Dr. Christian Laforsch & Prof. Dr. Holger Kress

PhD project: PlasticsFateE & CRC 1357 Microplastics, Subproject A04 | Cellular uptake of microparticles in relation to elementary particle properties

Research interests: Microplastics, human health, cellular internalisation, intracellular transport, immunology.


Faculty of Biology, Chemistry and Earth Sciences
Chair Animal Ecology I



Anja Ramsperger:Environmental Microplastics : How the Surface Properties of Microplastic Particles Determine their Particle-Cell Interactions. - Bayreuth: 2024. - 335 S.
(Dissertation, 2024, Universität Bayreuth, Bayreuther Graduiertenschule für Mathematik und Naturwissenschaften - BayNAT)

Maike Y. Adler, Insaf Issoual, Michael Rückert, Lisa Deloch, Carola Meier, Thomas Tschernig, Christoph Alexiou, Felix Pfister, Anja Ramsperger, Christian Laforsch, Udo S. Gaipl, Katharina Jüngert, Friedrich Paulsen: Effect of micro- and nanoplastic particles on human macrophages. In: Journal of Hazardous Materials, 471 (2024). - .

Simon Wieland, Anja Ramsperger, Wolfgang Groß, Moritz Lehmann, Thomas Witzmann, Anja Caspari, Martin Obst, Stephan Gekle, Günter K. Auernhammer, Andreas Fery, Christian Laforsch, Holger Kress: Nominally identical microplastic models differ greatly in their particle-cell interactions. In: Nature Communications, 15 (2024). - .


Susanne Saha, Christian Laforsch, Anja Ramsperger, Dennis Niebel: Mikroplastik und dermatologische Versorgung. In: Die Dermatologie, 74 (2023). - S. 27-33.

Anja Ramsperger, Enrico Bergamaschi, Marco Panizzolo, Ivana Fenoglio, Francesco Barbero, Ruud Peters, Anna Undas, Sebastian Purker, Bernd Giese, Carina R. Lalyer, Alba Tamargo, M. Victoria Moreno-Arribas, Hans-Peter Grossart, Dana Kühnel, Jana Dietrich, Friedrich Paulsen, Anani K. Afanou, Shan Zienolddiny-Narui, Stine Eriksen Hammer, Torunn Kringlen Ervik, Pål Graff, Bendik C. Brinchmann, Karl-Christian Nordby, Håkan Wallin, Matteo Nassi, Federico Benetti, Michela Zanella, Julian Brehm, Holger Kress, Martin G. J. Löder, Christian Laforsch: Nano- and microplastics : a comprehensive review on their exposure routes, translocation, and fate in humans. In: NanoImpact, 29 (2023). - .

Christian Laforsch, Anja Ramsperger, Sven Ritschar: Mikroplastik und der mögliche Einfluss auf die menschliche Gesundheit. In: Viviane Scherenberg, Johanne Pundt (Hrsg.): Klima-und Gesundheitsschutz : Planetary-Health-Lösungsansätze. - Bremen : Apollon University Press, 2023. - S. 131-158.


Simon Wieland, Aylin Balmes, Julian Bender, Jonas Kitzinger, Felix Meyer, Anja Ramsperger, Franz Roeder, Caroline Tengelmann, Benedik H. Wimmer, Christian Laforsch, Holger Kress: From properties to toxicity : comparing microplastics to other airborne microparticles. In: Journal of Hazardous Materials, 428 (2022). - .

Thomas Witzmann, Anja Ramsperger, Simon Wieland, Christian Laforsch, Holger Kress, Andreas Fery, Günter K. Auernhammer: Repulsive Interactions of Eco-corona-Covered Microplastic Particles Quantitatively Follow Modeling of Polymer Brushes. In: Langmuir, 38 (2022). - S. 8748-8756.

Anja Ramsperger, Julia Jasinski, Matthias Völkl, Thomas Witzmann, Marcel Meinhart, Valérie Jérôme, Winfried Kretschmer, Ruth Freitag, Jürgen Senker, Andreas Fery, Holger Kress, Thomas Scheibel, Christian Laforsch: Supposedly identical microplastic particles substantially differ in their material properties influencing particle-cell interactions and cellular responses. In: Journal of Hazardous Materials, 425 (2022). - .


Alfons Weig, Martin G. J. Löder, Anja Ramsperger, Christian Laforsch: In situ Prokaryotic and Eukaryotic Communities on Microplastic Particles in a Small Headwater Stream in Germany. In: Frontiers in Microbiology, 12 (2021). - .


Anja Ramsperger, Vinay Kumar Bangalore Narayana, Wolfgang Gross, John Mohanraj, Mukundan Thelakkat, Andreas Greiner, Holger Schmalz, Holger Kress, Christian Laforsch: Environmental exposure enhances the internalization of microplastic particles into cells. In: Science Advances, 6 (2020). - .

Christian Laforsch, Anja Ramsperger, Simona Mondellini, Tamara S. Galloway: Microplastics : A Novel Suite of Environmental Contaminants but Present for Decades. In: Franz-Xaver Reichl, Michael Schwenk (Hrsg.): Regulatory Toxicology. - Berlin : Springer, 2020. - S. 1-26.

James D. O´Connor, Anne M. Mahon, Anja Ramsperger, Benjamin Trotter, Paula E. Redondo-Hasselerharm, Albert A. Koelmans, Heather T. Lally, Sinéad Murphy: Microplastics in Freshwater Biota : A Critical Review of Isolation, Characterization, and Assessment Methods. In: Global Challenges, 4 (2020). - .

Anja Ramsperger, Anja C. Stellwag, Anja Caspari, Andreas Fery, Tillmann Lüders, Holger Kress, Martin G. J. Löder, Christian Laforsch: Structural Diversity in Early-Stage Biofilm Formation on Microplastics Depends on Environmental Medium and Polymer Properties. In: Water, 12 (2020). - .


Benjamin Trotter, Anja Ramsperger, Patricia Raab, Julia Haberstroh, Christian Laforsch: Plastic waste interferes with chemical communication in aquatic ecosystems. In: Scientific Reports, 9 (2019). - .


Hannes Imhof, Robert Sigl, Emilia Brauer, Sabine Feyl, Philipp Giesemann, Stefan Klink, Kathrin Leupolz, Martin G. J. Löder, Lena Löschel, Jan Missun, Sarah Muszynski, Anja Ramsperger, Isabella Schrank, Susan Speck, Sebastian Steibl, Benjamin Trotter, Isabel Winter, Christian Laforsch: Spatial and temporal variation of macro-, meso- and microplastic abundance on a remote coral island of the Maldives, Indian Ocean. In: Marine Pollution Bulletin, 116 (2017). - S. 340-347.


Faculty of Biology, Chemistry and Earth Sciences
Chair Animal Ecology I

Dr. Anja Ramsperger
PhD candidate Animal Ecology | Supervisor Prof. Dr. Christian LaforschPhD Candidate Biological Physics | Supervisor Prof. Dr. Holger Kress

Chair Animal Ecology I
Building B13, Room 1.02
University of Bayreuth
Universitätsstr. 30
95440 Bayreuth

Telefon: +49 (0) 921 55 2433

Fax: +49 (0) 921 55 2784

E-mail: anja.ramsperger@uni-bayreuth.de
ORCID: 0000-0002-2257-9610

Webmaster: Univ.Prof.Dr. Christian Laforsch

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